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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP3
All Species:
18.18
Human Site:
S470
Identified Species:
44.44
UniProt:
Q7Z494
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z494
NP_694972.3
1330
150864
S470
K
D
L
G
S
E
D
S
I
P
E
E
D
D
F
Chimpanzee
Pan troglodytes
XP_516758
2073
234018
S483
K
D
L
G
S
E
D
S
I
P
E
E
D
D
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863943
2040
230770
S450
K
D
L
G
S
E
D
S
I
P
E
E
D
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNH6
1324
150168
S466
K
D
G
G
R
E
D
S
T
P
E
E
D
D
F
Rat
Rattus norvegicus
XP_343462
1325
150597
S466
K
D
G
G
S
E
D
S
S
P
E
E
D
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514031
1275
145541
A440
Q
I
E
A
F
Q
Q
A
S
N
S
T
Y
E
L
Chicken
Gallus gallus
XP_418790
1315
149161
E452
K
D
L
G
N
K
E
E
S
T
A
P
E
E
E
Frog
Xenopus laevis
Q6AZT7
1300
148301
E445
K
D
E
S
A
T
M
E
D
D
D
Y
G
D
V
Zebra Danio
Brachydanio rerio
XP_691073
1303
148244
D454
V
E
E
R
E
E
E
D
S
G
D
V
L
W
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203493
1012
113472
S206
T
V
L
E
S
E
P
S
L
G
S
M
S
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
N.A.
61.5
N.A.
88.8
87.9
N.A.
78
83.9
76.9
69.9
N.A.
N.A.
N.A.
N.A.
30.9
Protein Similarity:
100
62.4
N.A.
63
N.A.
93.3
93.3
N.A.
86.2
90.7
86.5
82.9
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
N.A.
100
N.A.
80
86.6
N.A.
0
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
N.A.
100
N.A.
80
86.6
N.A.
26.6
60
33.3
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
0
0
0
0
50
10
10
10
20
0
50
60
10
% D
% Glu:
0
10
30
10
10
70
20
20
0
0
50
50
10
20
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
50
% F
% Gly:
0
0
20
60
0
0
0
0
0
20
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
30
0
0
0
0
0
0
% I
% Lys:
70
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
50
0
0
0
0
0
10
0
0
0
10
0
20
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
50
0
10
0
0
0
% P
% Gln:
10
0
0
0
0
10
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
50
0
0
60
40
0
20
0
10
0
0
% S
% Thr:
10
0
0
0
0
10
0
0
10
10
0
10
0
0
0
% T
% Val:
10
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _